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Among Korean adults aged 30 years, the prevalence of diabetes was 15.5% in 20212022 ( Historically, pathophysiologic models of diabetes have mainly focused on insulin deficiency or resistance, emphasizing -cell dysfunction

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Decreases over time varied by income groups, which may indicate different treatment patterns by income groups since 2020

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PDSS2 also attenuated ferroptosis in HCAECs by activating the antioxidant factor NF-E2-related factor 2 (Nrf2) (Yang et al., 2021)